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Sorafenib stimulates NRF2 expression in HCC cells, which boosts MT-1G expression, which prevents ferroptosis by inhibiting GSH depletion, which is one of the pathways associated in sorafenib resistance (87)
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Two open-label trials in PsA patients with obesity indicated improvements in disease activity (MDA) alongside metabolic benefits
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Changes in weight and nutrient intake can affect hormone levels and disrupt the hair growth cycle
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