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Improvements in FPG were significantly greater with exenatide (1.8 mmol/L) than with sitagliptin (0.9 mmol/L) but not significantly greater than with pioglitazone (1.5 mmol/L)

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However, patients with renal impairment, elevated homocysteine, choline metabolism disorders, or those taking anticoagulants should discuss potential interactions with their provider before starting