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Additionally, the mTOR, IL-17, NOD-like receptor and HIF-1 signaling pathways were involved (Supplementary Fig

Consequently, many metabolic disorders are associated with risk of epilepsy due in part to the brains high energy demand and reliance on energy production for homeostasis ( 4.1.2 Autism Spectrum disorders Surprisingly, there are few studies looking at sulforaphanes effectiveness in autism preclinical models considering most of the clinical trials (discussed later) for sulforaphane in neurological conditions focused on the ASD patient pool

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In contrast, the levels of several pro-inflammatory factors, such as IL-1, IL-6, IL-8, and leptin (Ke et al., 2021

The models were subsequently refined in Phenix