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In a study of elderly individuals, those with the highest glutathione levels were found to be the healthiest

doi: 10.1111/jgh.15899 169 SinghMPChoHJKimJ-TBaekKELeeHGKangSC

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We targeted our analysis on autosomal chromosomes, thus excluding 12,275 probes on sex chromosomes from the analysis

Treatment with SOD has experimentally been shown to reduce liver oxidative stress in diabetic animals.[79] SOD mimetic (Mn[II][pyane] Cl2) has successfully been used to treat diabetes in diabetic rats.[80] Chemically modified SOD (carboxymethylcellulose-SOD and poly methyl vinyl ether-co-maleic anhydride-SOD) was effective in treating diabetes and offers a therapeutic advantage in clinical use.[81] It has been demonstrated that extracellular SOD can act as a therapeutic agent to protect the progression of diabetic nephropathy.[82] Current limitations of SODs for therapeutic applications Due to the instability, high immunogenicity, low cellular uptake, and lesser circulation in vivo half-life of SOD, their clinical applications as therapeutic agents are very limited