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The overall discontinuation rate in clinical trials was approximately 8.1%, primarily due to nausea

[3] Additionally, there is also a black box warning due to risk of hepatotoxicity and pancreatitis

Most issues resolve with concentration reduction or application frequency adjustment

Glutamed OX is a medical nutritional supplement formulated specifically for the dietary management of patients with Sickle Cell Disease and oxidative stress-related NAD depletion in haemolytic disorders

Among them, oxidative stress refers to the excessive accumulation of reactive oxygen species (ROS) that leads to the imbalance of oxidants and antioxidants, oxidative stress has the ability to lead to mitochondrial dysfunction and lysosome dysfunction, and ultimately induces neurodegenerative disease (Caspersen et al., 2005