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Moreover, using probucol (500 mg/day, P.O for 6 months) for secondary prevention in patients with CHD lowered the incidence of the patients primary endpoint (cardiovascular disease death, hospitalization rate), which may be partly due to its strong antioxidant capacity [245]

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Interestingly, fisetin has been reported to restore tissue homeostasis, reduce age-related pathology, and extended median and maximum lifespan in wild-type mice (51)

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