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[DOI] [PubMed] [Google Scholar] 44.Mizuguchi Y., Chen J., Seshan S
Second, the 2mg starting dose is consistent across all arms above 1mg, providing a universal starting point regardless of target dose
Post-mortem examinations of MS patients brains showed typical inflammatory T cells, and macrophages perivascular infiltrates, along with myelin degradation and axons degeneration, but demyelinated lesions can occur anywhere within the brain and spinal cord, giving to the disease complexity, and heterogeneity of clinical signs, and symptoms (Kuhlmann et al., 2008)