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This was the first demonstration that a GLP-1R agonist produces cardiovascular benefit independent of glycaemic effects, expanding the research interest in GLP-1R agonism beyond metabolic and weight endpoints

Additionally, research suggests that GLP-1 agonists like semaglutide may have an anti-inflammatory effect that can further help lower the risk of heart attack or stroke in people with heart disease and obesity and/or type 2 diabetes

These two peptides represent the current gold standard for weight management and blood sugar control, but they work through different mechanisms and produce meaningfully different results in clinical trials

But its important to remember that neither medication is a magic weight-loss solution, Maselli says

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