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While gastrointestinal side effects are common, they are generally mild and transient, especially with proper patient education and dose titration
Zepbound (tirzepatide) injection, for subcutaneous use
The use of peptides can be risky if not done properly, as evidenced by a personal experience where a bunk peptide pen from overseas was used, resulting in severe side effects such as projectile vomiting and low blood sugar, which was a miserable experience 10s
Given that the most striking difference between BEST4+ cells in the small intestine versus the colon is CFTR expression in the small intestinal BEST4+ cells 21 , and our analysis further confirmed previous findings showing enrichment of CFTR High Expresser (CHE) populations in adult-type BEST4+ cells 16,29,62 (Supplementary Fig
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