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Bitots spot is a superficial, foamy or cheesy-looking lesion on the conjunctiva, typically appearing on the temporal (outer) side of the eye

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Regular screening every 1-2 years catches disease early in high-risk patientswaiting until symptoms appear often means 60-70% of kidney function is already lost

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[1] [2] This triple-receptor mechanism distinguishes it from currently approved agents such as semaglutide (a GLP-1 agonist) and tirzepatide (a dual GIP/GLP-1 agonist)