But this cycle can slow down, and dead cells may accumulate on the surface
Given the public concern caused by APAP hepatotoxicity, great efforts have been made to understand the mechanisms of its toxic effects
Our bodies are able to naturally produce GSH, however, production decreases with age, and we can quickly become overwhelmed with toxins and other offenders that deplete it
Companies often formulate with added antioxidants such as ferulic acid, or they may opt for more stable forms of vitamin C such as magnesium ascorbyl phosphate or 3-glyceryl ascorbate
Also, a potential oncogenic role of CHAC1 has been discovered, as its overexpression correlates with more advanced stages of breast cancer and poorer prognosis (Pankeviit-Bukauskien et al., 2023)