Goal: Trigger short, pulsatile releases of the bodys own growth hormone via the GHS-R1a receptor [1] [2] downstream effects on muscle, fat or recovery are not established in controlled human trials
A significant aspect of this study was the administration of a high dose (50 mg/kg) to evaluate the absorption profile effectively, overcoming the challenge posed by the endogenous production of GSH which could mask the effects of supplementation
The peptide binds copper with extraordinarily high affinity (pK = 16.44), which is roughly 10 million times higher than other tripeptides and comparable to albumins copper binding
Two of the largest RCTs assessed the risk of HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome (N=12,901 women) and found an increased risk of HELLP with calcium supplementation compared with placebo (RR 2.67, 95% CI: 1.05-6.82)
Additionally, L-carnitine may improve your bodys ability to use carbohydrates by increasing an enzyme known as AMPK