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Infrequent allergic reactions (IV administration) in humans and dogs (rash, pruritus, facial swelling, tachycardia, gastrointestinal signs)

However, one factor responsible for the limited effectiveness of B cell depletors in progressive MS may be resistance of leptomeningeal inflammation to even intrathecally administered agents for reasons that are not understood (Bhargava et al., 2019)

Lin A, et al

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