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Evidence also indicated a direct association between phases of migraine attacks and calcitonin gene-related peptide (CGRP), mitochondrial disorders, monoaminergic pathway, magnesium deficiency, and higher serum levels of glutamate (13, 14)

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Human clinical trials reported an average weight loss of 2.6 kg over 12 weeks versus 0.8 kg in placebo groups

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Widespread mitochondrial depletion via mitophagy does not compromise necroptosis