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Always follow the dosage and frequency recommended by your healthcare provider to safely boost energy, metabolism, and overall wellness

doi: 10.3389/fphar.2021.718147 Received 09 June 2021 Accepted 17 November 2021 Published 13 December 2021 Volume 12 - 2021 Edited by Fan Jiang, Shandong University, China Reviewed by Dechang Chen, Shanghai Jiao Tong University, China Ying Li, Xian Jiaotong University, China Updates Copyright 2021 Tepes, Gojkovic, Krezic, Zizek, Vranes, Madzar, Santak, Batelja, Milavic, Sikiric, Kocman, Simonji, Samara, Knezevic, Barisic, Lovric, Strbe, Kokot, Sjekavica, Kolak, Skrtic, Seiwerth, Boban Blagaic and Sikiric

B12 Deficiency Severity : If your B12 levels were extremely low, it may take longer for your body to adjust and for you to feel the effects

By blocking NNMT, it may support cellular NAD+ levels and metabolic function

At minimum, check metabolic panels, liver function, lipid profiles, and fasting glucose before starting and every 8-12 weeks during combination therapy