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Manufacturer savings programs: Many drug manufacturers offer discount cards, coupons, and patient assistance programs (PAP) to help reduce the cost of eligible patients

Again, this has the dual effect of rendering the (non-absorbed) drug initially ineffective, and then subjecting the patient to a bolus once the perfusion is restored

for pernicious anemia or low B12): Initial phase: 1 shot daily or every other day for 12 weeks Then: 1 shot weekly for 48 weeks Maintenance: 1 shot monthly (some may need it more often depending on absorption issues) Dose: Often 1000 mcg per injection (usually cyanocobalamin or methylcobalamin) Injection type: Usually intramuscular (IM) - or subcutaneous (SubQ) - 2

We suggest that this highlights the importance of proactive integrated physical and mental healthcare for all those suffering with HG, regardless of physiological severity