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Studies document effects on approximately 31.2% of human genes, representing over 4,000 genes with expression changes of 50% or greater

This is an interesting finding as research by Garnett et al

This particular variant is not only one of the most common among the increasing list of known rare pathogenic variants, but also one that benefits from a relatively long research history

J Biol Chem 266: 2897-2902, 1991

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