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Careful dosing, time-course experiments, and inclusion of vehicle controls, genetic controls and, where possible, endogenous stress conditions (hypoxia, nutrient deprivation) are therefore essential to avoid over-interpreting artefactual changes in lactylation [55, 155]

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Available at: [Accessed August 3, 2014]

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In March 2026, the FDA approved Wegovy HD, a high dose, 7.2 mg injectable formulation of semaglutide