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While cortisol, under normal conditions, supports glutamate clearance via astrocytic uptake and glutamine recycling, chronic cortisol elevation disrupts this balance, contributing to oxidative stress and neurodegeneration

To our knowledge, this is one of the first prospective case-control studies focusing exclusively on female FM patients

From the cover: correlations between apolipoprotein E 4 gene dose and brain-imaging measurements of regional hypometabolism

Switching between brand-name and compounded semaglutide requires careful dose matching

Apoptosis is primarily mediated through the caspase-3, caspase-9, and Bcl-2/Bax signaling pathways