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The breadth of the development program reflects confidence in the Phase 2 results and suggests that retatrutide, if approved, will be positioned as a comprehensive metabolic therapy rather than simply a weight loss drug

doi: 10.1093/humupd/dmx016 159 ChenCZhouYHuCWangYYanZLiZet al

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More importantly, the p53 expression level and p53 deacetylation rate were significantly increased in patients with nephrolithiasis and in CaOx crystal-treated HK-2 cells, as determined by analyzing the single-cell sequencing data and RNA-sequence data [279]