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This makes it easy to consume more than the recommended daily limit accidentally

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There are also people who combine it with micro needling

*Correspondence: Chen Chen, [email protected] Guo, [email protected] These authors have contributed equally to this work This article was submitted to Molecular Signalling and Pathways, a section of the journal Frontiers in Molecular Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The alanine substitution does not abolish copper binding but does modify the geometry, the binding affinity, and the biological characterization of the complex