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Concurrently, GSH reduces Fe 3 + to Fe 2 + , which activates S 2 O 8 2 to generate highly toxic sulfate (SO 4 ) and hydroxyl radicals, inducing coordinated ferroptosis and pyroptosis in lung cancer cells 219
In brief, parasites were regularly propagated in vivo via infection of C57BL/6 mice, and recovered from infected skin lesions by culturing in complete modified Schneiders Drosophila medium at 28 C and 5% CO 2 (Leitherer et al, 2017)
Vitamin C is also known to act as a prooxidant in vitro
Linking cellular stress responses to systemic homeostasis
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