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GLP-1RA activate the cAMP/PKA pathway leading to phosphorylation of sodium-hydrogen exchanger 3 (NHE3) in renal proximal tubular cells, increasing natriuresis and diuresis and lowering blood pressure

Gutirrez-Cuevas J, Santos A, Armendariz-Borunda J (2021) Pathophysiological molecular mechanisms of obesity: a link between MAFLD and NASH with cardiovascular diseases

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