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The liver converts ethanol to acetaldehyde through alcohol dehydrogenase (ADH), then to acetate through aldehyde dehydrogenase (ALDH)

Role of glutathione

Furthermore, the immunohistochemistry analysis evaluated the protective effects of the Au-PX-PLGA on dopaminergic neurons in the striatum and tyrosine hydroxylase, which is an essential enzyme in dopamine synthesis, served as the biomarker for dopaminergic neuron integrity