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This article systematically reviews the evidence for a role of glutathione redox in the aetiology of autism spectrum disorders and considers the research questions: 1) Is there an association between metabolites/co-factors/genes/enzymes of the -glutamyl cycle or trans-sulphuration pathway and autism spectrum disorders
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35 Alternatively, reporting of neurochemical levels relative to a reference neurochemical in the same voxel is a common approach, as measurements are technologically uncomplicated (only a single spectrum must be collected) and no correction for partial-volume effects is required
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