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Indeed, nitrotyrosine, a biomarker of reactive nitrogen species, has been shown to be increased in multiple tissues in children with ASD, including the brain ( 4 supplementation could help stabilize nitric oxide synthase as well as act as an antioxidant and improve monoamine neurotransmitter production

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Studies in diabetic and insulin-resistance paradigms often use IGF-1 and its analogues to better understand how insulin demand and glucose homeostasis can be influenced at the receptor and signaling level

Thus, its expression in hGMSCs would suggest a progression toward a neuronal lineage [1]