Always avoid injecting into areas that are bruised, red, or swollen
If you choose an oral GLP-1 medication and experience significant nausea or vomiting, consult your healthcare provider about using a backup contraceptive method during that period

Options include: Other GLP-1 receptor agonists (such as semaglutide or dulaglutide), though these share similar mechanisms and side effect profiles SGLT2 inhibitors (such as dapagliflozin or empagliflozin), which work through different mechanisms and have cardiovascular and renal benefits DPP-4 inhibitors (such as sitagliptin), which have a more modest effect on glycaemic control and weight Metformin (if not already prescribed), which remains the first-line treatment for type 2 diabetes according to NICE guidelines Insulin therapy (for patients requiring more intensive glycaemic control) For weight management specifically , alternatives to tirzepatide (Zepbound) include semaglutide 2.4 mg (Wegovy), which is approved by NICE for managing overweight and obesity, orlistat, or comprehensive lifestyle intervention programmes
Patients might describe generalized pruritus, widespread areas of tenderness or hyperesthesia, or skin reactivity in areas distant from injection sites
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