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Aggressive mixing, wrong water types, and improper temperatures can all damage the peptide structure through a process called denaturation, which permanently reduces or eliminates biological activity

BAs and UC In general, there is a balance between PBA and SBA, but gut microbiota dysbiosis disrupts it, and studies have shown that fecal PBA concentrations in UC patients are significantly higher than those in normal people, whereas SBA concentrations are significantly lower than those in normal people[107 ]