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The heterogeneity test did not reveal any differences between studies reporting data regarding the UPDRS I ( 2 =3.51, I 2 =0%, P=0.74)

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Under oxidative stress conditions, ROS are reduced by GSH with concomitant formation of the GSSG [37]

Abogadallah et al

The experiments were approved by the Italian Ministry of Health (Rome, Italy) and performed in agreement with the ARRIVE (Animals in Research: Reporting in vivo Experiments) guideline ( Figure 1 Drugs and Treatment Schedule VPA (Cayman Chemical, USA) was dissolved in saline at a concentration of 250 mg/ml and administered at a dose (500 mg/kg) and time (gestational day 12.5) that have been shown to induce autistic-like behavioral changes in the offspring ( , )