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(2022), who developed a rapid and sensitive method for analyzing alpha-tocopherol and its oxidative products using supercritical fluid extraction-supercritical fluid chromatography (SFE/SFC) coupled with proton transfer reaction ionization mass spectrometry (PTR-MS), enabling the separation and detection of alpha-tocopherol and its oxidation products, such as the alpha-tocopheroxyl radical and alpha-tocopheryl quinone, in approximately 3 min per sample with high sensitivity and resolution, even for isomers, without extensive sample preparation-a substantial improvement over traditional chromatographic methods that often involve complex processing and long separation times

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Together, these results reveal the recognition mechanism of GHRP-6 and diversify the peptide-binding mode for ghrelin receptor

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