In Alstrm syndrome, diabetes is common due to ALMS1 gene-related defects in -cell function and peripheral insulin signaling (129)
Notice whats NOT on this list: directly stimulating muscle protein synthesis through the androgen receptor
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Studies have demonstrated that GIP is associated with increased expression of pro-inflammatory cytokines and chemokines, while GIP infusion induces elevated levels of adipokines and pro-inflammatory cytokines in adipocytes in vitro [224,225,226,227,228,229]
Of this number of diabetics, roughly 90 to 95 percent have type 2 diabetes