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Nitric oxide modulates NMDA-induced increases in intracellular Ca 2+ in cultured rat forebrain neurons

Therapeutic targeting of proteostasis in metabolic diseases Targeting HSPs in metabolic diseases Given their central roles in metabolic homeostasis, heat shock proteins (HSPs) have emerged as attractive therapeutic targets in metabolic disease

Future Directions While preclinical data are compelling, human trials are needed to validate efficacy and dosing

EFSA NDA Panel, "L-carnitine and contribution to normal lipid metabolism: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006", EFSA Journal, 2018;16(1):5137

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