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Homocysteine metabolism in cardiovascular cells and tissues: implications for hyperhomocysteinemia and cardiovascular disease

Meanwhile, we also revealed the role of IHPC in resistance to chronic hypoxic injury, which provided a new perspective for the intervention of many hypoxia-related diseases

doi: 10.3389/fphar.2016.00385 31 WangMGuoZWangS

That is still manageable but approaching the upper limit of what is practical

Also addition of solution of glutathione (GSH) transferase in the reaction mixture caused a marked increase in the rate of reaction compared to the non-enzymatic, showing monobromobimane was a substrate for this enzyme ( Figure 1 )