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Sequence analysis of the GCL from multiple species indicates that these enzymes group into three distinct families (Figure 3A), as follows: non-plant eukaryotes (mammals, yeast, and trypanosomes), -proteobacteria ( Escherichia coli ), and plants ( Arabidopsis ) and -proteobacteria ( Rhizobium

There have been no large-scale, long-term studies to truly evaluate safety especially not for cancer risk

Chronic neuroinflammation appears to be a central source of cellular malfunction and destruction

Artificial intelligence-driven exposure modeling integrates multi-omics risk assessment data to predict individual susceptibility and optimize personalized intervention strategies (146)

Catalase proteins are envisaged as epicentres of an extended network of hydrogen-bonded water and H 2 O 2 molecules, stretching out from beyond the enzymes active sites, into the external cellular aqueous milieu