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However, in rare cases, very high doses may lead to mild side effects such as headaches, nausea, diarrhea, or skin reactions like itching and rashes
We then removed the cost report data of the 49 hospitals located in Puerto Rico from our dataset because we did not believe their cost structure reflected the costs of most hospitals paid under the OPPS, and, therefore, their inclusion may bias the calculation of hospital-weighted statistics
For example, the average female adult requires 2.4-2.8 mcg per day, but if you take a peek at the label of any given isolated B12 supplement, many contain upwards of 2,000 mcg per dose (12)
Because vitamin A is toxic in high doses, taking too much in the form of supplements can be dangerous
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