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Contents However, under some conditions in which NAPQI is not effectively detoxified (usually in case of paracetamol overdose), it causes severe damage to the liver

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Oxidative stress (OS) is characterized by an imbalance between oxidation and anti-oxidation mechanisms (enzymic and non-enzymic antioxidants), leading to an increase in oxidation intermediates such as reactive oxygen species (ROS) (5)

The slightly immunocompromised condition of G6PD-deficient patients may prevent severe inflammation, which may be consequently beneficial to patients