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The concerted efforts of synthetic chemists over the years have led to a common understating that organo-selenium compounds depending on their chemical structure can mimic GPx-like activity [71,72,73]

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They also restore gut microbial balance by inhibiting TLR4/NF-B signaling, activating Nrf2/HO-1 antioxidant pathways, repairing epithelial barriers, and re-establishing gut homeostasis