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SLU-PP-332 increases the expression of an estrogen receptor-related orphan receptor target gene, and gene expression and protein expression are measured in cell based assays and skeletal muscle cell lines to assess its effects

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15 Oesophageal motility is weakly measured using oesophageal manometry, which is particularly useful in patients exhibiting dysphagia or unexplained chest pain, especially when structural causes have been excluded

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The calculation of the free energy landscape is based on the potential of mean force (PMF), which is defined by G = k B Tln(x, y) where temperature is represented by T and k B is the Boltzmann constant