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Bifidobacterium breve and Bifidobacterium longum Attenuate Choline-Induced Plasma Trimethylamine N-Oxide Production by Modulating Gut Microbiota in Mice

Notably, the MC4R agonist setmelanotide (IMCIVREE) was recently approved by the US FDA to manage BBS-associated weight gain and is under evaluation for additional therapeutic effects in BBS patients (45, 46)

Although it cannot yet be determined whether vitamin B 12 deficiency plays a causal role in depression, it may be beneficial to screen for vitamin B 12 deficiency in older individuals as part of a medical evaluation for depression

doi: 10.1007/s10753-020-01233-w 168 LinC.-Y.YaoC.-A

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