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Our findings demonstrated elevated hypothalamic GLP-1R expression (Figure 4A) and preserved responsiveness to the acute GLP-1RA exendin-4 in Bbs5 / mice (Figure 4, LN), making them a compelling candidate for addressing BBS-associated metabolic dysfunction

Most people with type 1 diabetes should use regimens that mimic physiology as closely as possible, irrespective of the presentation

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