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Clinical studies have consistently shown that retatrutide, when used as an adjunct therapy to existing diabetes medications, significantly lowers HbA1c levelsa critical marker of long-term blood sugar control

Monti and colleagues in Uruguay ran a double-blind crossover of 25 nmol/kg over four nights and found that although several sleep measures moved in the expected direction, none differed significantly from baseline or placebo, and where differences did reach significance for NREM and stage 2 sleep, the same differences already existed at baseline

time to permanent discontinuation of trial product

A 12-month randomized trial also found significant increases in fat-free mass and limb lean mass following treatment

Schoell, S