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Conversely, discontinuation rates were increased to 33.7% (95% CI 33.4, 34.0) at 1 year and 50.6% (95% CI 50.3, 50.9) at 3 years when using a grace period of 60 days (ESM Table 4)

If youve been trying to lose weight doing diet and exercise for at least six months and not really seeing any results, I think its worth it to talk to a professional and see what your options are, says Dr

The VA data here is exactly what we keep seeing in real-world clinical practice: when patients with obesity get access to GLP-1 therapy and stick with it, the downstream metabolic and cardiovascular improvements are substantial and consistent

Psychiatry 118:110580

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