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In trials where semaglutide tablets was added on to metformin and/or sulfonylurea, basal insulin alone, or metformin in combination with basal insulin in patients with moderate renal impairment, severe hypoglycemia was not reported in any of the patients in the trial

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However, T-cell responses to conserved nonstructural regions especially the RTCare subdominant in detectable seropositive infections [62]