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Capping motifs in antimicrobial peptides and their relevance for improved biological activities

The HuCCT1 human bile duct carcinoma cell line was obtained from the Japanese Cancer Research Resources Bank

Any medication that affects glucose, lipid metabolism, growth hormone signaling, or beta-adrenergic activity could in theory interact, but evidence is absent

The blue Z-curve for the combined effect sizes of the 11 included trials crossed the horizontal green line of the traditional boundary and red TSA threshold

Key limitations of the existing evidence include: Small sample sizes in many studies Heterogeneous patient populations Variable dosing regimens (typically 35 grams daily) Short follow-up periods (often 4-12 weeks) Inconsistent outcome measures Potential publication bias favouring positive results Some studies have investigated combination approaches