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The most common include: Nausea, vomiting, diarrhea, constipation, abdominal pain Headache, dizziness, fatigue Indigestion, upset stomach, acid reflux Decreased appetite Injection site reactions Side effects are usually mild to moderate and tend to decrease over time

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In addition to reducing plasma DPP-4 activity, linagliptin increased plasma GLP-1 levels

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