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Violin, J
For the AMPK and adipocytokine/adiponectin pathways, recurrent nodes included G6PC, PPARG, and PPARGC1A, genes central to hepatic glucose regulation, adipose metabolism, and mitochondrial function, pathways consistently linked to GLP1RA metabolic benefits
Insulin In the current armamentarium for the treatment of type 2 diabetes, insulin is the most effective drug to rapidly correct hyperglycemia
included a figure showing the two-way influence between GLP-1 and metabolic/lifestyle factors
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