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Hydrophobic residues in p53 TAD2 are critical for interaction with FOXO4 FHD Based on the significance of both the TAD2 region and the C-terminus of p53 in interacting with the FOXO4 FHD, we attempted to develop an inhibitor targeting the FOXO4-p53 interaction

Such a combination not only ameliorated enduring pain, but also aided in mitigating bone marrow oedema across diverse stages of osteonecrosis of the femoral head

Application: standard stage - every 2 weeks (approx

An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17

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