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The carboxy-terminal portion of each chain defines a constant region primarily responsible for effector function

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Baseline characteristics were compared between groups using Wilcoxon Rank Sum and Fishers exact tests

Daniel Goldenberg, Hadassah-Hebrew University Medical Center) and wild-type (WT) mice (FVB/N, ENVIGO), males and females, were maintained under specific pathogen-free conditions with a 12-h-light-dark cycle and permitted ad libitum consumption of water and standard chow