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10.1021/cr200084z Chem

Sarah Ackley, a dementia epidemiologist at Brown University wasnt surprised the drug didnt slow cognitive decline

When monotherapy is not sufficient, sulfonylureas, meglitinides, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, glucagon-like peptide-1 (GLP-1) agonists (liraglutide, exenatide, semaglutide, dulaglutide) or insulin can be combined (171)

Malondialdehyde epitopes as mediators of sterile inflammation

This affects multiple organs, and results in consequences including demineralization of bone, hyperglycemia, and obesity, suggesting that GPRC6a plays a role in the coordination of nutrient sensing and metabolism in these tissues (141)