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What this means for patients The practical issue is not Should all patients stop GLP-1 drugs? The better question is: Do I already have diabetic retinopathy, and do I need a retinal exam or closer follow-up while my diabetes treatment is being intensified? Who Needs Extra Eye Monitoring

Patients were included if they had baseline bilateral pain radiographs demonstrating Kellgren and Lawrence grades of 1 to 3, as well as at least 2 years of follow-up before the initiation of GLP-1RA therapy for the sake of comparisons between groups

doi: 10.1038/s41598-018-28886-w 215 PanLAiXFuTRenLShangQLiGet al

2005;18(2):CD003639